Notes: Palmitoyl N-isopropylamide (PIA) is a synthetic analog of palmitoyl ethanolamide which incorporates isopropyl amide in place of the native ethanolamide. PIA does not bind appreciably to either CB1 or CB2 receptors.{9113} PIA inhibits both the transport (re-uptake) of tritiated AEA into intact cells, as well as the subsequent hydrolysis of AEA to arachidonate and ethanolamine, with 50% inhibition of FAAH-mediated hydrolysis at 10 µM.{9113}