Panaxadiol, CAS 19666-76-3

Formulation: A crystalline solid

Formal Name: 20R,25-epoxy-dammarane-3β,12β-diol

Purity: ≥98%

Formula Markup: C30H52O3

Formula Weight: 460,7

Shelf life (days): 1460

CAS Number: 19666-76-3

Notes: Panaxadiol is a triterpenoid sapogenin that has been found in P. ginseng and has diverse biological activities.{54756,54757,54758,54759} It inhibits the growth of HepG2 human hepatoma, A549 lung, MCF-7 breast, and HCT116 colon cancer cells (IC50s = 63.20, 40.88, 61.96, and 92.53 µM, respectively).{54756} Panaxadiol (30 mg/kg) reduces tumor growth in an HCT116 mouse xenograft model.{54757} It inhibits hepatitis B virus (HBV) DNA replication in HepG 2.2.15 cells with an IC50 value of 148.15 µM.{54758} Panaxadiol (50 mg/kg) also decreases the escape latency in the Morris water maze (MWM) in an APP/PS1 mouse model of Alzheimer's disease.{54759}

• Artikelnummer: CAY33233-5
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 33233-5
• Green Labware: Nein
• Verpackungseinheit: 5 mg
• Mengeneinheit: STK