Formulation: A solution in methyl acetate
Formal Name: 9α,11β-dihydroxy-15-oxo-13,14-dihydro-2,3,18,19-tetranor-prostan-1,20-dioic acid-18,18',19,19'-d4
Purity: ≥99% deuterated forms (d1-d4)
Formula Markup: C16H20D4O7
Formula Weight: 332,4
Shelf life (days): 180
Notes: PGDM-d4 is intended for use as an internal standard for the quantification of PGDM by GC- or LC-MS. PGD2 plays a pharmacological role in allergic and asthmatic anaphylaxis, normal physiological sleep and lowering of body temperature, as well as inhibits platelet aggregation and relaxes vascular smooth muscle.{580} PGDM is a major urinary metabolite of PGD2 with a unique lower sidechain that readily undergoes reversible cyclization.{35} It is used as a biomarker to assess endogenous production of PGD2.