Formulation: A crystalline solid
Formal Name: 3-(4-hydroxyphenyl)-1-(2,4,6-trihydroxyphenyl)-1-propanone
Purity: ≥98%
Formula Markup: C15H14O5
Formula Weight: 274,3
Shelf life (days): 1460
CAS Number: 60-82-2
Notes: Phloretin is a natural phenol which inhibits a variety of transporters. It inhibits the monocarboxylate transporters MCT1 and MCT2 (IC50 = 28 and 14 µM, respectively), restricting the rapid transport of monocarboxylates like lactate and pyruvate across the plasma membrane.{22891} Phloretin also blocks the sodium/D-glucose cotransporter (Ki = 86 µM) and the human concentrative nucleoside transporter 3 (Ki = 32 µM).{22894,22892}