Formulation: A solid
Formal Name: 5-[(1E)-2-phenylethenyl]-1,3-benzenediol
Purity: ≥98%
Formula Markup: C14H12O2
Formula Weight: 212,2
Shelf life (days): 1460
CAS Number: 22139-77-1
Notes: Pinosylvin is a stilbene originally isolated from pine heartwood that has diverse biological activities.{51006,51007,51008,51009,51010,51011} It activates sirtuin 1 (SIRT1) and induces glucose uptake in isolated rat L6 skeletal muscle myotubes.{51007} Pinosylvin reduces radial growth in a panel of 28 plant pathogenic fungi when used at a concentration of 100 μg/ml.{51008} It reduces expression of matrix metalloproteinase-2 (MMP-2), MMP-9, and membrane type 1-MMP in and inhibits migration of HT-1080 cells.{51009} Pinosylvin (10 mg/kg, i.p.) reduces the number of tumor nodules and lung tumor weight in a CT26 mouse xenograft model of metastatic colon cancer. It decreases hind paw volume and myeloperoxidase (MPO) activity in a rat model of adjuvant-induced arthritis.{51010} Pinosylvin also exhibits plant antifeedant activity against L. americanus (snowshoe hares).{51011}