Prednisolone Phosphate (sodium salt), CAS 125-02-0

Prednisolone Phosphate (sodium salt), CAS 125-02-0
Artikelnummer
CAY15933-10
Verpackungseinheit
10 g
Hersteller
Cayman Chemical

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Formulation: A crystalline solid

Formal Name: 11β,17-dihydroxy-21-(phosphonooxy)-pregna-1,4-diene-3,20-dione, disodium salt

Purity: ≥98%

Formula Markup: C21H27O8P • 2Na

Formula Weight: 484,4

Shelf life (days): 1460

CAS Number: 125-02-0

Notes: Prednisolone phosphate is a prodrug form of the synthetic glucocorticoid prednisolone (Item No. 20866) and a derivative of prednisone (Item No. 20677).{25865} It is hydrolyzed to prednisolone in vivo. Prednisolone phosphate (10 mg/kg), administered in long-circulating liposomes, decreases inflammation and the levels of IL-1β in the synovium, as well as reduces damage to the cartilage matrix in a mouse model of antigen-induced arthritis.{64484} It also reduces tumor growth in B16/F10 melanoma and C26 colon carcinoma mouse models when administered in long-circulating liposomes at a dose of 20 mg/kg.{64485} Formulations containing prednisolone phosphate have been used as anti-inflammatory or immunosuppressive agents.
Mehr Informationen
Artikelnummer CAY15933-10
Hersteller Cayman Chemical
Hersteller Artikelnummer 15933-10
Green Labware Nein
Verpackungseinheit 10 g
Mengeneinheit STK
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