Prednisone-d7

Formulation: A solid

Formal Name: 17-hydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-7,8S,9S,10R,12,13S,14S,15,16,17R-decahydro-3H-cyclopenta[a]phenanthrene-3,11(6H)-dione-2,4,6,6,9,12,12-d7

Purity: ≥99% deuterated forms (d1-d7)

Formula Markup: C21H19D7O5

Formula Weight: 365,5

Shelf life (days): 1460

Notes: Prednisone-d7 is intended for use as an internal standard for the quantification of prednisone (Item No. 20677) by GC- or LC-MS. Prednisone is a synthetic glucocorticoid with anti-inflammatory and immunosuppressant activities.{19136} It inhibits paw swelling induced by sodium urate in mice by 86% when administered at a dose of 12 mg/kg.{42622} Prednisone reduces release of IL-6, monocyte chemoattractant protein-2 (MCP-2), MCP-3, RANTES, and TNF-α in stented arteries in a rabbit model of atherosclerosis.{42623} Formulations containing prednisone have been used in the treatment of non-Hodgkin lymphoma as part of CHOP chemotherapy and as anti-inflammatory or immunosuppressive agents.

• Artikelnummer: CAY26459-500
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 26459-500
• Green Labware: Nein
• Verpackungseinheit: 500 µg
• Mengeneinheit: STK
• Methode: GC-MS, LC-MS, Isotopenmarkierung