Formulation: A crystalline solid
Formal Name: (2R,2'R,3R,3'S,4R)-2,2'-bis(3,4-dihydroxyphenyl)-3,3',4,4'-tetrahydro-[4,8'-bi-2H-1-benzopyran]-3,3',5,5',7,7'-hexol
Purity: ≥98%
Formula Markup: C30H26O12
Formula Weight: 578,5
Shelf life (days): 1460
CAS Number: 20315-25-7
Notes: Procyanidin B1 is a polyphenol flavonoid existing as a dimer of (+)-catechin (Item No. 70940) and (−)-epicatechin (Item No. 11807). It inhibits hepatitis C virus RNA replication (EC50 = 72 µM), while (+)-catechin and (−)-epicatechin do not, up to concentrations of 200 µM.{34659} Procyanidin B1 (10 µg/ml) prevents phosphorylation of ERK1/2 and the production of reactive oxygen species (ROS) in THP-1 cells.{34660} It decreases TNF-α, phosphorylated p38 MAPK, and NF-κB levels following LPS administration.{34661}