Prostaglandin D2, CAS 41598-07-6

Formulation: A crystalline solid

Formal Name: 9α,15S-dihydroxy-11-oxo-prosta-5Z,13E-dien-1-oic acid

Purity: ≥98%

Formula Markup: C20H32O5

Formula Weight: 352,5

Shelf life (days): 730

CAS Number: 41598-07-6

Notes: Prostaglandin D2 (PGD2) is the major eicosanoid product of mast cells and is released in large quantities during allergic and asthmatic anaphylaxis.{416} Mastocytosis patients produce excessive amounts of PGD2, which causes vasodilation, flushing, hypotension, and syncopal episodes.{416} PGD2 is also produced in the brain via an alternative pathway involving a soluble, secreted PGD-synthase also known as β-trace.{328,1185} In the brain, PGD2 produces normal physiological sleep and lowering of body temperature.{328,1185} Further pharmacological actions include inhibition of platelet aggregation and relaxation of vascular smooth muscle.{580} PGD2 inhibits human ovarian tumor cell proliferation with an IC50 of 6.8 µM.{1349}

• Artikelnummer: CAY12010-25
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 12010-25
• Green Labware: Nein
• Verpackungseinheit: 25 mg
• Mengeneinheit: STK