Prostaglandin D2 serinol amide, CAS 851761-42-7

Formulation: A solution in ethanol

Formal Name: N-[(2-hydroxy-1-hydroxymethyl)ethyl]-11-oxo-9α,15S-dihydroxy-prosta-5Z,13E-dien-1-amide

Purity: ≥95%

Formula Markup: C23H39NO6

Formula Weight: 425,6

Shelf life (days): 365

CAS Number: 851761-42-7

Notes: 2-Arachidonyl glycerol (2-AG) exhibits cannabinoid (CB) agonist activity at the CB1 receptor,{5306} is an important endogenous monoglyceride species,{6819} and is thus considered to be the natural ligand for the CB1 receptor. 2-AG can also be sequentially metabolized by COX-2 and specific PG synthases to form PG 2-glyceryl esters.{11045} In activated RAW 264.7 cells, PGD2 2-glyceryl ester is the primary product of 2-AG metabolism in the COX pathway.{11045} PGD2 serinol amide (PGD2-SA) is a stable analog of PGD2 2-glyceryl ester. Unlike PGD2 2-glyceryl ester and other fatty acyl 2-glyceryl esters, PGD2-SA will not isomerize to the less active primary (1-glyceryl) ester. The biological activity of PGD2-SA has not yet been determined.

• Artikelnummer: CAY10192-500
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 10192-500
• Green Labware: Nein
• Verpackungseinheit: 500 µg
• Mengeneinheit: STK
• Methode: Reinstoffe