Prostaglandin F2α-1-glyceryl ester-d5

Formulation: A solution in acetonitrile

Formal Name: 9α,11α,15S-trihydroxy-prosta-5Z,13E-dien-1-oic acid, 1-glyceryl ester-d5

Purity: ≥99% deuterated forms (d1-d5); ≤1% d0

Formula Markup: C23H35D5O7

Formula Weight: 433,6

Shelf life (days): 365

Notes: Prostaglandin F2α-1-glyceryl ester-d5 (PGF2α-1-glyceryl ester-d5) is intended for use as an internal standard for the quantification of PGF2α-1-glyceryl ester by GC- or LC-MS. 2-Arachidonoyl glycerol (2-AG) has been isolated from porcine brain, and has been characterized as the natural endocannabinoid ligand for the central cannabinoid receptor.{4614,5306} Incubation of 2-AG with cyclooxygenase 2 and specific PGH2 isomerases in cell cultures and isolated enzyme preparations results in PG glyceryl ester formation.{11045} The biosynthesis of PGH, PGD, PGE, PGF, and thromboxane A-2-glyceryl ester compounds have all been documented. The 2-glyceryl ester moiety equilibrates rapidly (within minutes) with the more stable 1-glyceryl ester, producing a 10:90 2:1-glyceryl ester mixture in typical aqueous media. While the stability and metabolism of PGF2α-1-glyceryl ester has been investigated, little is known about its intrinsic biological activity.{10555}

• Artikelnummer: CAY13883-50
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 13883-50
• Green Labware: Nein
• Verpackungseinheit: 50 µg
• Mengeneinheit: STK
• Methode: GC-MS, LC-MS, Isotopenmarkierung