Formulation: A solution in ethanol
Formal Name: 9α,11α,15S-trihydroxy-N-(2-hydroxyethyl)-prosta-5Z,13E-dien-1-amide
Purity: ≥98%
Formula Markup: C22H39NO5
Formula Weight: 397,5
Shelf life (days): 730
CAS Number: 353787-70-9
Notes: Prostaglandin F2α ethanolamide (PGF2α-EA) is produced by COX-2 metabolism of the endogenous cannabinoid, arachidonoyl ethanolamide (AEA), found in brain, liver, and other mammalian tissues.{2415} AEA can be metabolized directly by the sequential action of COX-2 and specific PG synthases to produce ethanolamide congeners of the classical PGs.{5089,11045} PGF2α-EA has also been reported to be biosynthesized by this mechanism when AEA was infused into the lung and liver of living mice. PGF2α-EA is a potent dilator (EC50 = 58 nM) of the cat iris sphincter, which is a model system for testing potential intraocular hypotensive agents.{8671}