Prostaglandin F2α methyl ester, CAS 33854-16-9

Formulation: A solution in methyl acetate

Formal Name: 9α,11α,15S-trihydroxy-prosta-5Z,13E-dien-1-oic acid, methyl ester

Purity: ≥98%

Formula Markup: C21H36O5

Formula Weight: 368,5

Shelf life (days): 365

CAS Number: 33854-16-9

Notes: Prostaglandin F2α methyl ester (PGF2α methyl ester) is an analog of PGF2α in which the C-1 carboxyl group has been esterified as the methyl ester. PGF2α methyl ester was one of the first PG esters shown to have ocular hypotensive activity.{8837} This compound continues to be a standard by which other ocular hypotensive PG prodrugs are evaluated. The methyl ester is about 4-5 times more potent than the free acid, PGF2α. This difference is attributed to improved corneal penetration, and a depot effect of prolonged retention of the ester form of the compound in ocular tissue. A 2.5 µg dose of PGF2α-OMe applied to the eyes of cats results in a 6-8 mm Hg reduction in IOP.{8837}

• Artikelnummer: CAY16011-5
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 16011-5
• Green Labware: Nein
• Verpackungseinheit: 5 mg
• Mengeneinheit: STK