Prunin, CAS 529-55-5

Formulation: A solid

Formal Name: (2S)-7-(β-D-glucopyranosyloxy)-2,3-dihydro-5-hydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one

Purity: ≥98%

Formula Markup: C21H22O10

Formula Weight: 434,4

Shelf life (days): 1460

CAS Number: 529-55-5

Notes: Prunin is a polyketide synthase-derived flavonoid glycoside that has been found in G. glabra and has diverse biological activities.{61558,61559,61560,61561,61562} It inhibits neuraminidase (NA) activity in oseltamivir-sensitive and -resistant H1N1 influenza strains (IC50s = 3 and 4.53 µM, respectively).{61559} Prunin (2 µM) scavenges DPPH radicals in a cell-free assay.{61560} It inhibits the activity of protein tyrosine phosphatase 1B (PTP1B; IC50 = 5.5 µM for the human enzyme) and increases insulin-induced glucose uptake in insulin-resistant HepG2 hepatocellular carcinoma cells in a concentration-dependent manner.{61561} Prunin inhibits the proliferation of, and induces apoptosis in, HL-60 leukemia cells.{61562}

• Artikelnummer: CAY34034-5
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 34034-5
• Green Labware: Nein
• Verpackungseinheit: 5 mg
• Mengeneinheit: STK