PtdIns-(3,4,5)-P3-fluorescein (triethylammonium salt)

Formulation: A lyophilized powder

Formal Name: 1-(1-octadecanoyl-fluorescein-2R-octanoylphosphatidyl)inositol-3,4,5-trisphosphate, heptatriethylammonium salt

Purity: ≥90%

Formula Markup: C46H54NO28P4 • 7C6H16N

Formula Weight: 1908,2

Shelf life (days): 1825

Notes: The phosphatidylinositols (PtdIns) phosphates represent a small precentage of total membrane phospholipids. However, they play a critical role in the generation and transmission of cellular signals.{4096,8344} PtdIns-(4,5)-P2 can be phosphorylated by phosphatidylinositol (PI)-3-kinase to make PtdIns-(3,4,5)-P3, which initiates an intricate signaling cascade that has been implicated in cancer.{12235} PtdIns-(3,4,5)-P3 fluorescein is a fluorescent probe for any protein with a high affinity binding interaction with inositol-(3,4,5)-triphosphate phospholipids, such as phosphatidylinositol 3-kinase, PTEN, or PH-domain-containing proteins.

• Artikelnummer: CAY10010383-100
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 10010383-100
• Green Labware: Nein
• Verpackungseinheit: 100 µg
• Mengeneinheit: STK
• Methode: Fluorescence