PtdIns-(4,5)-P2 (1,2-dipalmitoyl) (ammonium salt)

Formulation: A lyophilized powder

Formal Name: 1-(1,2R-dihexadecanoylphosphatidyl)inositol-4,5-bisphosphate, triammonium salt

Purity: ≥98%

Formula Markup: C41H78O19P3 • 3NH4

Formula Weight: 1022,1

Shelf life (days): 1825

Notes: The phosphatidylinositol phosphates represent a small percentage of total membrane phospholipids. However, they play a critical role in the generation and transmission of cellular signals.{243,8344} PtdIns-(4,5)-P2 incorporated into membrane lipids can bind to important proteins such as Group IV cPLA2 and PLCδ1, enhancing their adherence to the membrane and increasing the rate of substrate hydrolysis.{6009} PtdIns-(4,5)-P2 can be further phosphorylated to give triphosphates such as PtdIns-(3,4,5)-P3. It can also be cleaved by PI-specific PLC to give inositol triphosphates. The diacyl glycerol and IP3 generated by this PLC-cleavage are also part of a complex biochemical and signal transduction cascade which has not been entirely elucidated. For some additional reading, please see references {8344}, {3239}, and {8672}.

• Artikelnummer: CAY64924-500
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 64924-500
• Green Labware: Nein
• Verpackungseinheit: 500 µg
• Mengeneinheit: STK