(R)-(-)-Eicosapentaenyl-2'-Hydroxy-1'-Propylamide

Formulation: A solution in ethanol

Formal Name: N-((R)-2-hydroxypropyl)icosa-5Z,8Z,11Z,14Z,17Z-pentaenamide

Purity: ≥98%

Formula Markup: C23H37NO2

Formula Weight: 359,6

Shelf life (days): 365

Notes: N-Acyl ethanolamines (NAEs) have diverse biological actions that are strongly affected by the associated acyl group. Eicosapentaenoyl ethanolamide (EPEA) has potential signaling roles in aging, cancer, inflammation, and neurological development.{21496,19917,19740,19623} At least some of EPEA’s effects are mediated through cannabinoid (CB) receptors, while some NAEs also act as vanilloid receptor agonists.{21496,19780} (R)-(−)-Eicosapentaenyl-2’-hydroxy-1’-propylamide is a homolog of EPEA, characterized by the addition of an (R)-β-methyl group at the terminal ethanolamine carbon. A similar modification of arachidonoyl ethanolamide (Item No. 90050) to produce R-2 methanandamide (Item No. 90074) imparts diminished affinity for the CB receptor as well as reduced metabolic stability.{1092} The physiological actions of this compound have not been evaluated.

• Artikelnummer: CAY9001226-1
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 9001226-1
• Green Labware: Nein
• Verpackungseinheit: 1 mg
• Mengeneinheit: STK