R-Palmitoyl-(2-methyl) Ethanolamide, CAS 179951-56-5

Formulation: A crystalline solid

Formal Name: N-(2R-hydroxypropyl)-hexadecanamide

Purity: ≥98%

Formula Markup: C19H39NO2

Formula Weight: 313,5

Shelf life (days): 1460

CAS Number: 179951-56-5

Notes: R-Palmitoyl-(2-methyl) ethanolamide (RP-2ME) is a metabolically stable analog of the anti-inflammatory endogenous cannabinoid, palmitoyl ethanolamide (PEA). PEA is an endogenous cannabinoid found in brain, liver, and other mammalian tissues.{2415} PEA has also been isolated from egg yolk, and found to have anti-anaphylactic and anti-inflammatory activity in vitro.{1633} RP-2ME is a synthetic analog of PEA which incorporates an (R)-methyl group vicinal to the alcohol on the ethanolamine moiety. RP-2ME inhibits FAAH-mediated hydrolysis of AEA by 54% at a concentration of 100 µM.{9113} It also has weak CB receptor affinity, in that 100 µM inhibits agonist binding (1 nM CP 55,940 or WIN 55,212-2) only 26% and 15.5% at the human CB1 and CB2 receptors, respectively.{9113}

• Artikelnummer: CAY90357-50
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 90357-50
• Green Labware: Nein
• Verpackungseinheit: 50 mg
• Mengeneinheit: STK