Resolvin D1 methyl ester, CAS 937738-63-1

Formulation: A solution in ethanol

Formal Name: 7S,​8R,​17S-​trihydroxy-​​4Z,​9E,​11E,​13Z,​15E,​19Z-​docosahexaenoic acid, methyl ester

Purity: ≥97%

Formula Markup: C23H34O5

Formula Weight: 390,5

Shelf life (days): 365

CAS Number: 937738-63-1

Notes: Resolvin D1 (RvD1; Item No. 10012554) is produced physiologically from the sequential oxygenation of docosahexaenoic acid (Item No. 90310) by 15- and 5-lipoxygenase (Item No. 60402).{13989} It reduces human polymorphonuclear leukocyte transendothelial migration, the earliest event in acute inflammation, with an EC50 value of ~30 nM.{15718} RvD1 methyl ester is a methyl ester version of the free acid that may act as a lipophilic prodrug form that will alter its distribution and pharmacokinetic properties. The methyl ester moiety is susceptible to cleavage by intracellular esterases, leaving the free acid.

• Artikelnummer: CAY9001815-100
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 9001815-100
• Green Labware: Nein
• Verpackungseinheit: 100 µg
• Mengeneinheit: STK