Resolvin D2 n-3 DPA, CAS 2093111-29-4

Formulation: A solution in ethanol

Formal Name: 7S,16R,17S-trihydroxy-8E,10Z,12E,14E,19Z-docosapentaenoic acid

Purity: ≥98%

Formula Markup: C22H34O5

Formula Weight: 378,5

Shelf life (days): 365

CAS Number: 2093111-29-4

Notes: Resolvin D2 n-3 DPA (RvD2 n-3 DPA) is a specialized pro-resolving mediator (SPM).{33485} It is formed from docosapentaenoic acid (n-3 DPA; Item Nos. 90165 / 21907), an intermediate in the conversion of eicosapentaenoic acid (Item Nos. 90110 / 90110.1 / 21908) to docosahexaenoic acid (Item Nos. 90310 / 17950), in human leukocytes. RvD2 n-3 DPA (1 nM) reduces TNF-α-induced chemotaxis and adhesion of isolated human neutrophils. In vivo, RvD2 n-3 DPA (100 ng/animal; i.v.) reduces peritoneal neutrophil infiltration and exudate levels of IL-6 and chemokine (C-C motif) ligand 2 (CCL2) in a mouse model of zymosan-induced inflammation.

• Artikelnummer: CAY34482-100
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 34482-100
• Green Labware: Nein
• Verpackungseinheit: 100 µg
• Mengeneinheit: STK