Scutellarein, CAS 529-53-3

Formulation: A crystalline solid

Formal Name: 5,6,7-trihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one

Purity: ≥98%

Formula Markup: C15H10O6

Formula Weight: 286,2

Shelf life (days): 1460

CAS Number: 529-53-3

Notes: Scutellarein is a flavone that has been isolated from S. baicalensis and has antioxidant, enzyme inhibitory, anti-inflammatory, and antiproliferative biological activities.{37603,37604,37605,37606,37607,37608} It has antioxidant activity in a total reactive antioxidant potential (TRAP) assay when used at a concentration of 1 μg/ml.{37604} Scutellarein inhibits sucrose hydrolysis by rat intestinal α-glucosidase and ATPase activity of the severe acute respiratory syndrome (SARS) coronavirus helicase nsP13 (IC50s = 12 and 0.86 μM, respectively).{37605,37606} It decreases nitric oxide (NO) release and mRNA expression of inducible NO synthase (iNOS) and TNF-α induced by LPS in RAW 264.7 macrophages when used at a concentration of 50 μM.{37607} In vivo, scutellarein (0.5 μg/g) decreases tumor weight and volume in an HT-1080 human fibrosarcoma mouse xenograft model.{37608}

• Artikelnummer: CAY24977-50
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 24977-50
• Green Labware: Nein
• Verpackungseinheit: 50 mg
• Mengeneinheit: STK