Sophoraflavanone G, CAS 97938-30-2

Formulation: A solid

Formal Name: (2S)-2-(2,4-dihydroxyphenyl)-2,3-dihydro-5,7-dihydroxy-8-[(2R)-5-methyl-2-(1-methylethenyl)-4-hexen-1-yl]-4H-1-benzopyran-4-one

Purity: ≥95%

Formula Markup: C25H28O6

Formula Weight: 424,5

Shelf life (days): 1460

CAS Number: 97938-30-2

Notes: Sophoraflavanone G is a flavonoid that has been found in S. flavescens and has diverse biological activities.{62339,62340,62341,62342} It is active against 21 strains of methicillin-resistant S. aureus (MRSA; MICs = 3.13-6.25 µg/ml) and inhibits the activities of α-glucosidase and β-amylase (Kis = 5.6 and 30.6 µM, respectively).{62339,62340} Sophoraflavanone G is cytotoxic to HL-60 and HepG2 cancer cells (IC50s = 12.5 and 13.3 µM, respectively) and induces apoptosis in HL-60 cells when used at concentrations of 10 or 25 µM.{62341} It reduces LPS-induced production of prostaglandin E2 (PGE2; Item No. 14010) in RAW 264.7 cells when used at concentrations ranging from 1 to 50 µM.{62342} Sophoraflavanone G (250 mg/kg) inhibits carrageenan-induced paw edema in rats.

• Artikelnummer: CAY34755-5
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 34755-5
• Green Labware: Nein
• Verpackungseinheit: 5 mg
• Mengeneinheit: STK