Sphingosine-d7 (d18:1), CAS 1246304-34-6

Formulation: A crystalline solid

Formal Name: (2S,3R,4E)-2-amino-4-octadecene-16,16,17,17,18,18,18-d7-1,3-diol

Purity: ≥99% deuterated forms (d1-d7)

Formula Markup: C18H30D7NO2

Formula Weight: 306,5

Shelf life (days): 730

CAS Number: 1246304-34-6

Notes: Sphingosine-d7 (d18:1) is intended for use as an internal standard for the quantification of sphingosine (d18:1) (Item No. 10007907) by GC- or LC-MS. Sphingosine (d18:1) is formed primarily from the breakdown of ceramide.{13592} Sphingosine (d18:1) inhibits protein kinase C and phosphatidic acid phosphohydrolase, whereas it activates phospholipase D and diacylglycerol (DAG) kinase.{13592} Phosphorylation of sphingosine (d18:1) by sphingosine kinases 1 and 2 (SPHK1, SPHK2) produces sphingosine-1-phosphate, a potent bioactive lipid that exhibits a broad spectrum of biological activities including cell proliferation, survival, migration, cytoskeletal organization, and morphogenesis.{11895,12477,10628}

• Artikelnummer: CAY22786-1
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 22786-1
• Green Labware: Nein
• Verpackungseinheit: 1 mg
• Mengeneinheit: STK
• Methode: GC-MS, LC-MS, Isotopenmarkierung