Formulation: A solid
Formal Name: (2S,3R,E)-aminooctadec-4-ene-15,15,16,16,17,17,18,18,18-d9-1,3-diol
Purity: ≥99% deuterated forms (d1-d9)
Formula Markup: C18H28D9NO2
Formula Weight: 308,6
Shelf life (days): 1460
CAS Number: 2377379-55-8
Notes: Sphingosine-d9 is intended for use as an internal standard for the quantification of sphingosine (Item No. 10007907) by GC- or LC-MS. Sphingosine is formed primarily from the breakdown of ceramide.{13592} Sphingosine inhibits protein kinase C and phosphatidic acid phosphohydrolase, whereas it activates phospholipase D and diacylglycerol (DAG) kinase.{13592} Phosphorylation of sphingosine by sphingosine kinases 1 and 2 (SPHK1, SPHK2) produces sphingosine-1-phosphate, a potent bioactive lipid that exhibits a broad spectrum of biological activities including cell proliferation, survival, migration, cytoskeletal organization, and morphogenesis.{11895,12477,10628} [Matreya, LLC. Catalog No. 2079]