Tectoridin, CAS 611-40-5

Formulation: A solid

Formal Name: 7-(β-D-glucopyranosyloxy)-5-hydroxy-3-(4-hydroxyphenyl)-6-methoxy-4H-1-benzopyran-4-one

Purity: ≥98%

Formula Markup: C22H22O11

Formula Weight: 462,4

Shelf life (days): 1460

CAS Number: 611-40-5

Notes: Tectoridin is a polyketide synthase-derived flavonoid glycoside and phytoestrogen that has been found in B. chinensis and has diverse biological activities.{54947,54943,54944,54945,54946} It scavenges hydroxyl radicals in a cell-free assay (IC50 = 178 µg/ml) and inhibits the formation of thiobarbituric acid reactive substances (TBARS) in egg yolk (IC50 = 86 µg/ml).{54943} Tectoridin (200 µM) activates thyroid hormone receptor- or estrogen receptor-mediated transcription in GH3 rat pituitary and MCF-7 human breast cancer cells, respectively, in reporter assays.{54944} It inhibits the production of prostaglandin E2 (PGE2; Item No. 14010) induced by thapsigargin (Item No. 10522) in isolated rat peritoneal macrophages when used at concentrations of 10 and 30 µM.{54945} Tectoridin (60 mg/kg) inhibits trabecular bone loss in a mouse model of osteoporosis induced by ovariectomy.{54946}

• Artikelnummer: CAY33969-10
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 33969-10
• Green Labware: Nein
• Verpackungseinheit: 10 mg
• Mengeneinheit: STK