tetranor-PGDM lactone-d6

Formulation: A solution in methyl acetate

Formal Name: 5α-hydroxy-7,11-dioxo-2,3,4,5-tetranor-prostan-1,14-dioic acid-16,16,17,17,18,18-d6

Purity: ≥99% deuterated forms (d1-d6)

Formula Markup: C16H16D6O6

Formula Weight: 316,4

Shelf life (days): 180

Notes: tetranor-PGDM lactone-d6 contains six deuterium atoms at the 16, 16', 17, 17', 18 and 18' positions. It is intended for use as an internal standard for the quantification of tetranor-PGDM lactone by GC- or LC-mass spectrometry. PGD2 plays a pharmacological role in allergic and asthmatic anaphylaxis, normal physiological sleep and lowering of body temperature, as well as inhibits platelet aggregation and relaxes vascular smooth muscle.{580} tetranor-PGDM is an abundant urinary metabolite of PGD2 that is detectable both in human and mouse and, as such, is used as a biomarker of PGD2 biosynthesis.{15162} tetranor-PGDM lactone is a closed form of tetranor-PGDM. The formation of tetranor-PGDM lactone in biological samples has not been evaluated.

• Artikelnummer: CAY11213-100
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 11213-100
• Green Labware: Nein
• Verpackungseinheit: 100 µg
• Mengeneinheit: STK
• Methode: GC-MS, LC-MS, Isotopenmarkierung