Tibolone, CAS 5630-53-5

Formulation: A crystalline solid

Formal Name: 17α-hydroxy-7α-methyl-19-norpregn-5(10)-en-20-yn-3-one

Purity: ≥98%

Formula Markup: C21H28O2

Formula Weight: 312,5

Shelf life (days): 1460

CAS Number: 5630-53-5

Notes: Tibolone is an estrogen-like compound used for the treatment of the symptoms associated with menopausal transition (i.e., climacteric symptoms) and also for the treatment of osteoporosis.{12450} Three major metabolites of tibolone are responsible for its tissue selective mechanism of action. Conversion into 3α- and 3β-hydroxy-tibolone results in estrogenic effects in brain, vagina, and bone. The Δ4 isomer has progestrogenic and androgenic effects and does not cause estrogenic stimulation in the endometrium.{12450} A two-year longitudinal study indicates that low doses (1.25-2.5 mg) of tibolone effectively relieve climacteric symptoms and prevent loss of bone mass in early postmenopausal women.{12449}

• Artikelnummer: CAY10006321-250
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 10006321-250
• Green Labware: Nein
• Verpackungseinheit: 250 mg
• Mengeneinheit: STK
• Methode: Reinstoffe