Trichostatin A, CAS 58880-19-6

Formulation: A crystalline solid

Formal Name: 7-[4-(dimethylamino)phenyl]-N-hydroxy-4,6R-dimethyl-7-oxo-2E,4E-heptadienamide

Purity: ≥95%

Formula Markup: C17H22N2O3

Formula Weight: 302,4

Shelf life (days): 1460

CAS Number: 58880-19-6

Notes: Trichostatin A is a potent, reversible inhibitor of class I, II, and IV histone deacetylases (HDACs). In human Jurkat T cells, trichostatin A arrests cell cycle progression in G1 and inhibits the activity of HDAC1 with an IC50 value of 70 nM.{8150} Trichostatin A selectively inhibits the removal of acetyl groups from the amino-terminal lysine residues of core histones, which modulates the access of transcription factors to the underlying genomic DNA.{4011}

• Artikelnummer: CAY89730-5
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 89730-5
• Green Labware: Nein
• Verpackungseinheit: 5 mg
• Mengeneinheit: STK