Ursodeoxycholic Acid (sodium salt), CAS 31687-65-7

Formulation: A crystalline solid

Formal Name: 3α,7β-dihydroxy-5β-cholan-24-oic acid, sodium salt

Purity: ≥98%

Formula Markup: C24H39O4 • xNa

Formula Weight: 414,6

Shelf life (days): 1460

CAS Number: 31687-65-7

Notes: Ursodeoxycholic acid (UDCA) is a secondary bile acid formed via epimerization of chenodeoxycholic acid (CDCA; Item No. 10011286).{48224,48225} UDCA is also a metabolite of lithocholic acid (LCA; Item No. 20253) in human liver microsomes.{48226} It inhibits taurocholic acid (Item No. 16215) uptake in HeLa cells expressing recombinant sodium/taurocholate cotransporting polypeptide (NTCP) with an IC50 value of 3.6 μM.{24182} UDCA (50 μM) inhibits apoptosis induced by deoxycholic acid (DCA; Item Nos. 20756 / 18231) or ethanol in primary rat hepatocytes.{48227} Dietary administration of UDCA blocks DCA-induced increases in the number of TUNEL-positive hepatocytes in rats. Formulations containing UDCA have been used in the treatment of primary biliary cirrhosis.

• Artikelnummer: CAY15121-5
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 15121-5
• Green Labware: Nein
• Verpackungseinheit: 5 g
• Mengeneinheit: STK