Mitochondrial Fusion Promoter M1, CAS 219315-22-7

Formulation: A solid

Formal Name: 2-(2,4,6-trichlorophenyl)hydrazone, 1-(5-chloro-2-hydroxyphenyl)-ethanone

Purity: ≥95%

Formula Markup: C14H10Cl4N2O

Formula Weight: 364,1

Shelf life (days): 1460

CAS Number: 219315-22-7

Notes: Mitochondrial fusion promoter M1 is a promoter of mitochondrial fusion.{69654} It induces elongation of mitochondria in mitofusin-1 knockout (Mfn1-/-) or Mfn2-/- mouse embryonic fibroblasts (MEFs; EC50s = 5.3 and 4.42 µM, respectively) and protects against MPP+-induced mitochondrial fragmentation and cytotoxicity in SH-SY5Y cells when used at a concentration of 5 µM. M1 (1 µM) reduces apoptosis and inhibits decreases in testosterone levels induced by the organophosphate triphenyl phosphate in TM3 mouse Leydig cells.{69655} In vivo, mitochondrial fusion promoter M1 (2 mg/kg) improves novel object recognition deficits induced by the antitumor antibiotic doxorubicin (Item No. 15007) in rats.{69656}

• Artikelnummer: CAY39909-5
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 39909-5
• Verpackungseinheit: 5 mg
• Mengeneinheit: STK