1-Deoxymannojirimycin (hydrochloride), CAS 73465-43-7

Product Description: 1-Deoxymannojirimycin hydrochloride is a selective class I α1,2-mannosidase inhibitor with an IC50 of 20 μM. 1-Deoxymannojirimycin hydrochloride is also a N-linked glycosylation inhibitor and inhibits HIV‐1 strains. 1-Deoxymannojirimycin hydrochloride has antiviral activity[1][2].

Applications: COVID-19-anti-virus

Formula: C6H14ClNO4

References: [1]F Vallee, et al. Structural Basis for Catalysis and Inhibition of N-glycan Processing Class I Alpha 1,2-mannosidases. J Biol Chem. 2000 Dec 29;275(52):41287-98./[2]Jan Balzarini, et al. The alpha(1,2)-mannosidase I Inhibitor 1-deoxymannojirimycin Potentiates the Antiviral Activity of Carbohydrate-Binding Agents Against Wild-Type and Mutant HIV-1 Strains Containing Glycan Deletions in gp120. FEBS Lett. 2007 May 15;581(10):2060-4.

CAS Number: 73465-43-7

Molecular Weight: 199.63

Compound Purity: 99.06

Research Area: Infection

Solubility: DMSO : 50 mg/mL (ultrasonic)/H2O : 100 mg/mL (ultrasonic)

Target: HIV;Influenza Virus

• Artikelnummer: MEXHY-W009783-100
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-W009783-100
• Green Labware: Nein
• Verpackungseinheit: 100 mg
• Mengeneinheit: STK