1-Methyl-2-((4Z,7Z)-4,7-tridecadienyl)-4(1H)-quinolone, CAS 120693-53-0

Product Description: 1-Methyl-2-[(4Z,7Z)-4,7-tridecadienyl]-4(1H)-quinolone, a quinolone alkaloid, is a diacylglycerol acyltransferase inhibitor and angiotensin II receptor blocker, with IC50s of 20.1 μM and 34.1 μM, respectively. 1-Methyl-2-[(4Z,7Z)-4,7-tridecadienyl]-4(1H)-quinolone shows potent anti-Helicobacter pylori activity with the MIC of 10 μg/mL[1][2][3].

Applications: Metabolism-sugar/lipid metabolism

Formula: C23H31NO

References: [1]Rho TC, et, al. Anti-Helicobacter pylori activity of quinolone alkaloids from Evodiae fructus. Biol Pharm Bull. 1999 Oct;22(10):1141-3./[2]Lee HS, et, al. Inhibition of angiotensin II receptor binding by quinolone alkaloids from Evodia rutaecarpa. Phytotherapy Research. 1998 May; 12(3): 212-214./[3]Ko JS, et, al. Quinolone alkaloids, diacylglycerol acyltransferase inhibitors from the fruits of Evodia rutaecarpa. Planta Med. 2002 Dec;68(12):1131-3./[4]Adams M, et, al. Inhibition of leukotriene biosynthesis by quinolone alkaloids from the fruits of Evodia rutaecarpa. Planta Med. 2004 Oct;70(10):904-8.

CAS Number: 120693-53-0

Molecular Weight: 337.50

Research Area: Infection; Metabolic Disease; Cardiovascular Disease

Solubility: 10 mM in DMSO

Target: Acyltransferase;Angiotensin Receptor;Bacterial

• Artikelnummer: MEXHY-N9530-5
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-N9530-5
• Green Labware: Nein
• Verpackungseinheit: 5mg
• Mengeneinheit: STK