11R(12S)-EET, CAS 123931-38-4

Product Description: 11R(12S)-EET is a cis-epoxytrienoic acid (EETs) derivative that is metabolized by cytoplasmic cyclooxygenases. Studies have shown that 14(R), 15(S)-, 11(S),12(R)-, and 8(S),9(R)-EETs are metabolized at significantly higher rates than their enantiomers. Enzyme-catalyzed hydration revealed that water addition was non-regioselective for the 11,12-EET enantiomers, whereas water addition occurred primarily at the C9 position for both enantiomers of 8,9-EET. These results suggest that the metabolic properties of 11R(12S)-EET and other EET enantiomers in enzyme-catalyzed processes are significantly affected by their stereostructures[1].

Formula: C20H32O3

References: [1]Zeldin DC, et al. Metabolism of epoxyeicosatrienoic acids by cytosolic epoxide hydrolase: substrate structural determinants of asymmetric catalysis. Arch Biochem Biophys. 1995 Jan 10;316(1):443-51.

CAS Number: 123931-38-4

Molecular Weight: 320.47

Research Area: Others

Target: Others

• Artikelnummer: MEXHY-N12962A-0
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-N12962A-0
• Verpackungseinheit: Get quote
• Mengeneinheit: STK