13-Hydroxyisobakuchiol, CAS 178765-49-6

Product Description: Hydroxyisobakuchiol (Delta3,2-Hydroxylbakuchiol), an analog of Bakuchiol (HY-N0235) isolated from Psoralea corylifolia (L.), is a potent monoamine transporter inhibitor. 13-Hydroxyisobakuchiol is more selective for the dopamine transporter (DAT) (IC50=0.58 μM) and norepinephrine transporter (NET) (IC50=0.69 μM) than for the serotonin transporter (SERT) (IC50=312.02 μM). 13-Hydroxyisobakuchiol has the potential for the research of disorders such as Parkinson's disease and depression[1].

Applications: Neuroscience-Neurodegeneration

Formula: C18H24O2

References: [1]Gang Zhao, et al. Bakuchiol analogs inhibit monoamine transporters and regulate monoaminergic functions. Biochem Pharmacol. 2008 May 1;75(9):1835-47.

CAS Number: 178765-49-6

Molecular Weight: 272.38

Research Area: Neurological Disease

Solubility: 10 mM in DMSO

Target: Dopamine Transporter;Monoamine Transporter

• Artikelnummer: MEXHY-N7506-25
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-N7506-25
• Green Labware: Nein
• Verpackungseinheit: 25mg
• Mengeneinheit: STK