(±)14,15-Epoxyeicosatrienoic acid, CAS 197508-62-6

Product Description: (±)14,15-Epoxyeicosatrienoic acid ((±)14(15)-EET) is the Cytochrome P450 metabolite of arachidonic acid. While CYP3A4 may be involved in breast cancer cell growth, (±)14,15-Epoxyeicosatrienoic acid may promote mitosis and anchorage-dependent cloning through STAT3 affected by CYP3A4. (±)14,15-Epoxyeicosatrienoic acid exhibits STAT3-dependent cell growth promotion and may also participate in the autocrine/paracrine pathway that drives cell growth[1][2].

Applications: Cancer-programmed cell death

Formula: C20H32O3

References: [1]Mitra R, et al. CYP3A4 mediates growth of estrogen receptor-positive breast cancer cells in part by inducing nuclear translocation of phospho-Stat3 through biosynthesis of (±)-14,15-epoxyeicosatrienoic acid (EET). J Biol Chem. 2011 May 20;286(20):17543-59./[2]Zhang DX, et al. Acetylcholine-induced relaxation and hyperpolarization in small bovine adrenal cortical arteries: role of cytochrome P450 metabolites. Endocrinology. 2004 Oct;145(10):4532-9.

CAS Number: 197508-62-6

Molecular Weight: 320.47

Compound Purity: 99.0

Research Area: cancer

Solubility: 10 mM in DMSO

Target: Cytochrome P450

• Artikelnummer: MEXHY-150084-50UG
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-150084-50UG
• Verpackungseinheit: 50 μg（312.04 μM * 500 μL in Ethanol）
• Mengeneinheit: STK