2,6-Dimethylquinoline, CAS 877-43-0

Product Description: 2,6-Dimethylquinoline, a nature constituent from the roots of Peucedantu praeruptorum, is a CYP1A2 inhibitor with an IC50 of 3.3 µM. 2,6-Dimethylquinoline also inhibits CYP2B6 activity with an IC50 of 480 µM[1][2][3].

Applications: Metabolism-sugar/lipid metabolism

Formula: C11H11N

References: [1]Laura E Korhonen, et al. Predictive three-dimensional quantitative structure-activity relationship of cytochrome P450 1A2 inhibitors. J Med Chem. 2005 Jun 2;48(11):3808-15./[2]L E Korhonen, et al. New potent and selective cytochrome P450 2B6 (CYP2B6) inhibitors based on three-dimensional quantitative structure-activity relationship (3D-QSAR) analysis. Br J Pharmacol. 2007 Apr;150(7):932-42./[3]Cun Zhang, et al. Studies on chemical constituents from roots of Peucedanum praeruptorum II. Zhongguo Zhong Yao Za Zhi. 2006 Aug;31(16):1333-5.

CAS Number: 877-43-0

Molecular Weight: 157.22

Compound Purity: 99.95

Research Area: Others

Solubility: DMSO : 100 mg/mL (ultrasonic)

Target: Cytochrome P450

• Artikelnummer: MEXHY-W010195-10.1
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-W010195-10.1
• Green Labware: Nein
• Verpackungseinheit: 10mM/1mL
• Mengeneinheit: STK