2-Benzoxazolinone, CAS 59-49-4

Product Description: 2-Benzoxazolinone is an anti-leishmanial agent with an LC50 of 40 μg/mL against L. donovani[1]. A building block in chemical synthesis. 1,3-Benzoxazol-2(3H)-one derivatives have antimicrobial activity against a selection of Gram-positive, Gram-negative bacteria and yeasts[3]. Derivatives as anti-quorum sensing agent[4].

Applications: COVID-19-immunoregulation

Formula: C7H5NO2

References: [1]Kapil A, et al. Leishmanicidal activity of 2-benzoxazolinone from Acanthus illicifolius in vitro. Planta Med. 1994 Apr;60(2):187-8./[2]Batish DR, et al. 2-Benzoxazolinone (BOA) induced oxidative stress, lipid peroxidation and changes in some antioxidant enzyme activities in mung bean (Phaseolus aureus). Plant Physiology and Biochemistry 44(11-12):819-27/[3]Krawiecka M, et al. Synthesis and biological activity of novel series of 1,3-benzoxazol-2(3H)-one derivatives. Acta Pol Pharm. 2013 Mar-Apr;70(2):245-53./[4]Miandji AM, et al. Synthesis and biological activities of some 1,3-benzoxazol-2(3H)-one derivatives as anti-quorum sensing agents. Arzneimittelforschung. 2012 Jul;62(7):330-4.

CAS Number: 59-49-4

Molecular Weight: 135.12

Compound Purity: 99.96

Research Area: Infection

Solubility: DMSO : 100 mg/mL (ultrasonic)/H2O : 3.85 mg/mL (ultrasonic)

Target: Parasite

• Artikelnummer: MEXHY-W015818-10.1
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-W015818-10.1
• Green Labware: Nein
• Verpackungseinheit: 10mM/1mL
• Mengeneinheit: STK