2-Ketoglutaric acid, CAS 328-50-7

Product Description: 2-Ketoglutaric acid (Alpha-Ketoglutaric acid) is an intermediate in the production of ATP or GTP in the Krebs cycle. 2-Ketoglutaric acid also acts as the major carbon skeleton for nitrogen-assimilatory reactions. 2-Ketoglutaric acid is a reversible inhibitor of tyrosinase (IC50=15 mM)[1].

Applications: Metabolism-sugar/lipid metabolism

Formula: C5H6O5

References: [1]Huergo LF, et al. The Emergence of 2-Oxoglutarate as a Master Regulator Metabolite. Microbiol Mol Biol Rev. 2015 Dec;79(4):419-35./[2]Gou L, et al. The effect of alpha-ketoglutaric acid on tyrosinase activity and conformation: Kinetics and molecular dynamics simulation study. Int J Biol Macromol. 2017 Dec;105(Pt 3):1654-1662.

CAS Number: 328-50-7

Molecular Weight: 146.10

Compound Purity: 99.90

Research Area: Others

Solubility: DMSO : 250 mg/mL (ultrasonic)/H2O : 50 mg/mL (ultrasonic)

Target: Endogenous Metabolite;Tyrosinase

• Artikelnummer: MEXHY-W013636-500
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-W013636-500
• Green Labware: Nein
• Verpackungseinheit: 500 mg
• Mengeneinheit: STK