3,4,5-Trimethoxycinnamic acid, CAS 90-50-6

Product Description: 3,4,5-Trimethoxycinnamic acid is a phenylpropanoid isolated from the roots of Polygala tenuifoliaWILLD, with anti-stress effect, prolonging the sleeping time in animals[1][2]. 3,4,5-Trimethoxycinnamic acid increases expression of GAD65 and γ-subunit of GABAA receptor, but shows no effect on the amounts of α-, β-subunits[2].

Applications: Neuroscience-Neuromodulation

Formula: C12H14O5

References: [1]Kawashima K, et al. Anti-stress effects of 3,4,5-trimethoxycinnamic acid, an active constituent of roots of Polygala tenuifolia (Onji). Biol Pharm Bull. 2004 Aug;27(8):1317-9./[2]Lee CI, et al. 3,4,5-Trimethoxycinnamic acid (TMCA), one of the constituents of Polygalae Radix enhances pentobarbital-induced sleeping behaviors via GABAAergic systems in mice. Arch Pharm Res. 2013 Oct;36(10):1244-51.

CAS Number: 90-50-6

Molecular Weight: 238.24

Compound Purity: 99.86

Research Area: Neurological Disease

Solubility: DMSO : 100 mg/mL (ultrasonic)

Target: Endogenous Metabolite;GABA Receptor

• Artikelnummer: MEXHY-W012123-50G
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-W012123-50G
• Green Labware: Nein
• Verpackungseinheit: 50 g
• Mengeneinheit: STK