3-Hydroxyisovalerylcarnitine, CAS 99159-87-2

Product Description: 3-Hydroxyisovalerylcarnitine is a carnitine derivative. 3-Hydroxyisovaleryl carnitine in plasma may serve as a novel biomarker of biotin deficiency in humans, with its concentration increasing with biotin deficiency. Biotin deficiency reduces the activity of biotin-dependent 3-methylcrotonyl-CoA carboxylase, hinders the conversion of 3-methylcrotonyl-CoA into 3-methylglutaconyl-CoA, and impairs the leucine catabolism pathway; resulting in plasma 3-Hydroxyisovalerylcarnitine concentrations rise[1].

Formula: C12H23NO5

References: [1]Horvath TD, et al. Quantitative measurement of plasma 3-hydroxyisovaleryl carnitine by LC-MS/MS as a novel biomarker of biotin status in humans. Anal Chem. 2010 May 15;82(10):4140-4.

CAS Number: 99159-87-2

Molecular Weight: 261.31

Compound Purity: 99.0

Research Area: Metabolic Disease

Solubility: 10 mM in DMSO

Target: Endogenous Metabolite

• Artikelnummer: MEXHY-N11200-1
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-N11200-1
• Green Labware: Nein
• Verpackungseinheit: 1 mg
• Mengeneinheit: STK