4,6-O-Ethylidene-α-D-glucose, CAS 13224-99-2

Product Description: 4,6-O-ethylidene-α-D-glucose (Ethylidene-glucose), a glucose derivative, is a competitive exofacial binding-site inhibitor on glucose transporter 1 (GLUT1) with a Ki of 12 mM for wild-type 2-deoxy-D-glucose transport[1][2][3].

Applications: Metabolism-sugar/lipid metabolism

Formula: C8H14O6

References: [1]M Hashiramoto, et al. Site-directed Mutagenesis of GLUT1 in Helix 7 Residue 282 Results in Perturbation of Exofacial Ligand Binding. J Biol Chem. 1992 Sep 5;267(25):17502-7./[2]Malay Patra, et al. A Potent Glucose-Platinum Conjugate Exploits Glucose Transporters and Preferentially Accumulates in Cancer Cells. Angew Chem Int Ed Engl. 2016 Feb 12;55(7):2550-4./[3]G F Baker, et al. The Permeation of Human Red Cells by 4,6-O-ethylidene- -D-glucopyranose (Ethylidene Glucose). J Physiol. 1973 May;231(1):129-42.

CAS Number: 13224-99-2

Molecular Weight: 206.19

Compound Purity: 98.0

Research Area: Metabolic Disease

Solubility: DMSO : 100 mg/mL (ultrasonic)/H2O : 125 mg/mL (ultrasonic)

Target: Endogenous Metabolite;GLUT

• Artikelnummer: MEXHY-N7433-10.1
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-N7433-10.1
• Green Labware: Nein
• Verpackungseinheit: 10mM/1mL
• Mengeneinheit: STK