4-Hydroxycoumarin, CAS 1076-38-6

Product Description: 4-Hydroxycoumarin is an orally active coumarin derivative, one of the most versatile heterocyclic scaffolds, often used in the synthesis of various organic compounds. 4-Hydroxycoumarin possesses both electrophilic and nucleophilic properties. 4-Hydroxycoumarin is an HIV protease inhibitor and tyrosine kinase inhibitor. 4-Hydroxycoumarin has anti-inflammatory, antibacterial and anti-tumor effects[1][2][3][4].

Applications: COVID-19-anti-virus

Formula: C9H6O3

References: [1]Mohammadi Ziarani G, et al. The molecular diversity scope of 4-hydroxycoumarin in the synthesis of heterocyclic compounds via multicomponent reactions. Mol Divers. 2019 Jan 29. doi: 10.1007/s11030-019-09918-7./[2]Velasco-Velázquez MA, et al. 4-Hydroxycoumarin disorganizes the actin cytoskeleton in B16-F10 melanoma cells but not in B82 fibroblasts, decreasing their adhesion to extracellular matrix proteins and motility. Cancer Lett. 2003 Aug 20;198(2):179-86./[3]Salinas-Jazmín N, et al. Antimetastatic, antineoplastic, and toxic effects of 4-hydroxycoumarin in a preclinical mouse melanoma model. Cancer Chemother Pharmacol. 2010 Apr;65(5):931-40./[4]Luchini AC, et al. Intestinal anti-inflammatory activity of coumarin and 4-hydroxycoumarin in the trinitrobenzenesulphonic acid model of rat colitis. Biol Pharm Bull. 2008 Jul;31(7):1343-50.

CAS Number: 1076-38-6

Molecular Weight: 162.14

Compound Purity: 99.96

Research Area: Infection

Solubility: DMSO : 100 mg/mL (ultrasonic)

Target: Bacterial;Endogenous Metabolite

• Artikelnummer: MEXHY-N6856-50G
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-N6856-50G
• Green Labware: Nein
• Verpackungseinheit: 50 g
• Mengeneinheit: STK