4′-Hydroxywogonin, CAS 57096-02-3

Product Description: 4′-Hydroxywogonin (8-Methoxyapigenin), a flavonoid, could be isolated from a variety of plants including Scutellaria barbata and Verbena littoralis. 4′-Hydroxywogonin has anti-inflammatory activity via TAK1/IKK/NF-κB, MAPKs and PI3/AKT signaling pathways. 4′-Hydroxywogonin inhibits angiogenesis by disrupting PI3K/AKT signaling. 4′-Hydroxywogonin inhibits cell proliferation and induces apoptosis[1][2][3].

Applications: COVID-19-immunoregulation

Formula: C16H12O6

References: [1]Fan C, et, al. 4'-Hydroxywogonin suppresses lipopolysaccharide-induced inflammatory responses in RAW 264.7 macrophages and acute lung injury mice. PLoS One. 2017 Aug 8;12(8):e0181191.

CAS Number: 57096-02-3

Molecular Weight: 300.26

Research Area: Cancer; Inflammation/Immunology; Cardiovascular Disease

Solubility: 10 mM in DMSO

Target: Akt;Apoptosis;Bcl-2 Family;Caspase;IKK;Interleukin Related;NF-κB;p38 MAPK;PI3K;Reactive Oxygen Species;TNF Receptor

• Artikelnummer: MEXHY-N1904-1
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-N1904-1
• Verpackungseinheit: 1 mg
• Mengeneinheit: STK