(±)5-HEPE, CAS 83952-40-3

Product Description: (±)5-HEPE is produced by non-enzymatic oxidation of EPA. It contains equal amounts of 5(S)-HEPE and 5(R)-HEPE. The biological activity of (±)5-HEPE is likely mediated by one of the individual isomers, most commonly the 5(S) isomer in mammalian systems. EPA can be metabolized to 5-HEPE in human and bovine neutrophils, and human eosinophils, which is further metabolized to 5-oxoEPE and LTB5. The 5-series metabolites of EPA, namely 5-HEPE, 5-oxoEPE, and LTB5, have significantly decreased biological effects compared to the arachidonic acid-derived metabolites.

Applications: Metabolism-protein/nucleotide metabolism

Formula: C20H30O3

References: [1]Powell, et al. Formation of a 5-oxo metabolite of 5,8,11,14,17-eicosapentaenoic acid and its effects on human neutrophils and eosinophils. J. Lipid Res. 36, 2590-2598 (1995).

CAS Number: 83952-40-3

Molecular Weight: 318.45

Research Area: Metabolic Disease

Target: Others

• Artikelnummer: MEXHY-N7801-0
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-N7801-0
• Verpackungseinheit: Get quote
• Mengeneinheit: STK