6-Benzoylheteratisine, CAS 99759-48-5

Product Description: 6-Benzoylheteratisine is an Aconitum alkaloid with potential neuroprotective activity. 6-Benzoylheteratisine can antagonize tetrodotoxin, inhibit the increase of [Na+]i, [Ca2+]i and glutamate release, and block sodium channels. 6-Benzoylheteratisine has an inhibitory effect on the neuronal activity underlying epileptiform burst discharge[1][2].

Applications: Neuroscience-Neuromodulation

Formula: C29H37NO6

References: [1]Gutser UT, et al. The alkaloid 6-benzoylheteratisine inhibits voltage-gated Na+ channels in rat brain synaptosomes. Neuropharmacology. 1998 Sep;37(9):1139-46./[2]Ameri A. Effects of the alkaloids 6-benzoylheteratisine and heteratisine on neuronal activity in rat hippocampal slices. Neuropharmacology. 1997 Aug;36(8):1039-46.

CAS Number: 99759-48-5

Molecular Weight: 495.61

Compound Purity: 99.66

Research Area: Neurological Disease

Solubility: 10 mM in DMSO

Target: Sodium Channel

• Artikelnummer: MEXHY-N9404-5
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-N9404-5
• Green Labware: Nein
• Verpackungseinheit: 5 mg
• Mengeneinheit: STK