6-Hydroxyflavone, CAS 6665-83-4

Product Description: 6-Hydroxyflavone is a naturally occurring flavone, with anti-inflammatory activity. 6-Hydroxyflavone exhibits inhibitory effect towards bovine hemoglobin (BHb) glycation. 6-Hydroxyflavone can activate AKT, ERK 1/2, and JNK signaling pathways to effectively promote osteoblastic differentiation. 6-Hydroxyflavone inhibits the LPS-induced NO production[1] [2].

Applications: COVID-19-immunoregulation

Formula: C15H10O3

References: [1]Das S, et al. Characterization of non-covalent binding of 6-hydroxyflavone and 5,7-dihydroxyflavone with bovine hemoglobin: Multi-spectroscopic and molecular docking analyses. J Photochem Photobiol B. 2018 Jan;178:40-52./[2]Lai CH, et al. Effects of 6-Hydroxyflavone on Osteoblast Differentiation in MC3T3-E1 Cells. Evid Based Complement Alternat Med. 2014;2014:924560./[3]Wang X, et al. 6-Hydroxyflavone and derivatives exhibit potent anti-inflammatory activity among mono-, di- and polyhydroxylated flavones in kidney mesangial cells. PLoS One. 2015 Mar 19;10(3):e0116409.

CAS Number: 6665-83-4

Molecular Weight: 238.24

Compound Purity: 99.95

Research Area: Inflammation/Immunology

Solubility: DMSO : 125 mg/mL (ultrasonic)

Target: Akt;ERK;JNK

• Artikelnummer: MEXHY-N7110-100
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-N7110-100
• Green Labware: Nein
• Verpackungseinheit: 100 mg
• Mengeneinheit: STK