7,3',4'-Tri-O-methylluteolin, CAS 29080-58-8

Product Description: 7,3',4'-Tri-O-methylluteolin (5-Hydroxy-3',4',7-trimethoxyflavone), a flavonoid compound, possesses potent anti-inflammatory effects in LPS-induced macrophage cell line mediated by inhibition of release of inflammatory mediators, NO, PGE2, and pro-inflammatory cytokines. 7,3',4'-Tri-O-methylluteolin significantly induces reduction in the mRNA expressions of inducible nitric oxide synthase and cyclooxygenase-2[1].

Applications: Metabolism-protein/nucleotide metabolism

Formula: C18H16O6

References: [1]Sudha, A, et al. Protective effect of 5-hydroxy-3′,4′,7-trimethoxyflavone against inflammation induced by lipopolysaccharide in RAW 264.7 macrophage: in vitro study and in silico validation. Medicinal Chemistry Research, 2016,25(9), 1754–1767.

CAS Number: 29080-58-8

Molecular Weight: 328.32

Compound Purity: 99.28

Research Area: Inflammation/Immunology

Solubility: DMSO : 20 mg/mL (ultrasonic)

Target: COX;Interleukin Related;TNF Receptor

• Artikelnummer: MEXHY-N7012-10
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-N7012-10
• Green Labware: Nein
• Verpackungseinheit: 10 mg
• Mengeneinheit: STK