Product Description: 8(S),9(R)-EET is an eicosanoid product of Arachidonic acid (AA; HY-109590) by cytochromes P450. 8(S),9(R)-EET dilates canine epicardial arterioles in a concentration-dependent manner with an EC50 value of 121 nM[1][2].
Applications: Neuroscience-Neuromodulation
Formula: C20H32O3
References: [1]D C Zeldin, et al. Epoxygenase pathways of arachidonic acid metabolism. J Biol Chem. 2001 Sep 28;276(39):36059-62./[2]Y Zhang, et al. EET homologs potently dilate coronary microvessels and activate BK(Ca) channels. Am J Physiol Heart Circ Physiol. 2001 Jun;280(6):H2430-40.
CAS Number: 123931-39-5
Molecular Weight: 320.47
Research Area: Cardiovascular Disease
Target: Drug Metabolite