α-Spinasterol, CAS 481-18-5

Product Description: α-Spinasterol, isolated from Melandrium firmum, has antibacterial activity[1]. α-Spinasterol is a transient receptor potential vanilloid 1 (TRPV1) antagonist, has anti-inflammatory, antidepressant, antioxidant and antinociceptive effects. α-Spinasterol inhibits COX-1 andCOX-2 activities with IC50 values of 16.17 μM and 7.76 μM, respectively[2].

Applications: COVID-19-immunoregulation

Formula: C29H48O

References: [1]Brusco I, et al. α-Spinasterol: a COX inhibitor and a transient receptor potential vanilloid 1 antagonist presents an antinociceptive effect in clinically relevant models of pain in mice. Br J Pharmacol. 2017 Dec;174(23):4247-4262./[2]Yang X, et al. A novel method for synthesis of α-spinasterol and its antibacterial activities in combination with ceftiofur. Fitoterapia. 2017 Jun;119:12-19.

CAS Number: 481-18-5

Molecular Weight: 412.69

Compound Purity: 99.15

Research Area: Infection; Neurological Disease

Solubility: DMF : 2 mg/mL (ultrasonic;warming;heat to 60°C)

Target: Bacterial;COX;TRP Channel

• Artikelnummer: MEXHY-N6962-10
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-N6962-10
• Green Labware: Nein
• Verpackungseinheit: 10 mg
• Mengeneinheit: STK