Acivicin (hydrochloride), CAS 161922-40-3

Product Description: Acivicin hydrochloride (AT-125 hydrochloride), a natural product produced by Streptomyces sviceus, is a γ-glutamyl transpeptidase (GGT) inhibitor. Acivicin hydrochloride can across the blood-brain barrier and has anti-cancer, anti-parasitic properties[1][2].

Applications: COVID-19-immunoregulation

Formula: C5H8Cl2N2O3

References: [1]Delphine Waniusiow, et al. Toluene-induced hearing loss in acivicin-treated rats. Neurotoxicol Teratol. May-Jun 2008;30(3):154-60./[2]Kreuzer J, et al. Target discovery of acivicin in cancer cells elucidates its mechanism of growth inhibition. Chem Sci. 2014 Dec 1;6(1):237-245. Epub 2014 Sep 26./[3]Chikhale EG, et al. Carrier-mediated transport of the antitumor agent acivicin across the blood-brain barrier. Biochem Pharmacol. 1995 Mar 30;49(7):941-5.

CAS Number: 161922-40-3

Molecular Weight: 215.03

Compound Purity: 99.14

Research Area: Cancer; Infection

Solubility: DMSO : 100 mg/mL (ultrasonic)

Target: Parasite

• Artikelnummer: MEXHY-W016586A-100
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-W016586A-100
• Green Labware: Nein
• Verpackungseinheit: 100 mg
• Mengeneinheit: STK